Custom Synthesis
Our expertise includes:
  • mg to Kg Scale Synthesis
  • API's & Building Blocks
  • Amino Acids & Peptides
  • Asymmetric Synthesis
  • Speciality Fine Chemicals
Chemical Sourcing
We can provide access to:
  • Natural Products
  • Carbohydrates
  • Prostaglandins
  • Nucleotides
  • Fermentation Products
Chemical Analysis
Our analytical services include:
  • Multinuclear NMR
  • HPLC
  • MS & LC-MS
  • Optical Rotation
  • IR Spectrometry

Expertise

The synthetic capability of our chemistry team is vast

We synthesise the majority of the 3,000 item catalogue range in-house and as a result our chemists are highly experienced in preparing biologically active molecules that are both structurally and synthetically diverse.

For full details of the Tocris Bioscience catalogue range, including activity data, references and purity information, please visit www.tocris.com.

Examples from our catalogue to illustrate the diversity of our work
2531 | Ganaxalone
Ganaxalone : Potent positive allosteric modulator of GABAA receptors
Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors.
2476 | SR 11302
SR 11302 : Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumour effects in vivo
Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumour effects in vivo; antitumour agent.
2416 | BIBX 1382
BIBX 1382: Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase
Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
2592 | TCB-2
TCB-2 : High affinity 5-HT2A receptor agonist. Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2
High affinity 5-HT2A receptor agonist. Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors.
2453 | LY 379268
LY 379268 : Highly selective group II mGlu receptor agonist that displays > 80-fold selectivity over group I and group III
Highly selective group II mGlu receptor agonist that displays > 80-fold selectivity over group I and group III receptors.
2623 | Oxaliplatin
Oxaliplatin : Antitumour agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA repli
Antitumour agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription.