 |
 |
 |
Synthesis
Sourcing
Analytical
|
| Home | Services | Facilities | Expertise | Why Tocris? | Contact |
Expertise
The synthetic capability range of our chemistry team is vast. We synthesise the majority of our 1800 catalogue products in-house and as a result our chemists are highly experienced in preparing biologically active molecules that are both structurally and synthetically diverse.
To see what we mean, click here to browse our catalogue.
To illustrate the diversity of our work, below are a few recent catalogue additions:
|
|
|
Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors.
|
Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumour effects in vivo; antitumour agent.
|
Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
|
|
High affinity 5-HT2A receptor agonist. Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors.
|
Antitumour agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription.
|
Highly selective group II mGlu receptor agonist that displays > 80-fold selectivity over group I and group III receptors.
|